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Nonmem weighted optimization
Nonmem weighted optimization













Results: In the present work a definition of a suitable probability space is given, so that a rigorous definition of absorbed dose is possible. This is not done in report 85 by the ICRU, mentioned above. A random variable is a mathematical function, and it cannot be defined without specifying its domain of definition which is a probability space. Methods: Absorbed dose is defined in terms of the random variable specific energy imparted. The purpose of the present work is to give a rigorous definition of absorbed dose. The most recent and authoritative definition of absorbed dose is given by the International Commission on Radiation Units and Measurements (ICRU) in ICRU Report 85. Purpose: The quantity absorbed dose is used extensively in all areas concerning the interaction of ionizing radiation with biological organisms, as well as with matter in general.

nonmem weighted optimization

There was no measurable effect of the dose rate on the tensile properties for accelerated electron exposures. Total doses less than 2.5 MGy did not significantly change the tensile properties of the film whereas doses higher than 2.5 MGy significantly reduced elongation-to-failure.

nonmem weighted optimization

Total absorbed doses from 1 kGy to 100 MGy and absorbed dose rates from 0.01 MGy/hr to 100 MGy/hr were investigated, where 1 Gy equals 100 rads. The threshold values of total absorbed dose for causing changes in tensile properties of a polyetherimide film and the limitations of the absorbed dose rate for accelerated-exposure evaluation of the effects of electron radiation in geosynchronous orbit were studied.

nonmem weighted optimization

Absorbed dose thresholds and absorbed dose rate limitations for studies of electron radiation effects on polyetherimides















Nonmem weighted optimization